1. Identify the study type
A review synthesizes previous work; an original study reports new data. The title alone does not establish evidence strength or methodological quality.
Catalog entries
Scientific references
Explore publications associated with catalog entries and use this guide to read each paper in context. Links come from the public Nexus bibliography; they document research questions, not the identity, quality, or results of a Nexus product for sale.
129 linked publications · 15 catalog entries
01 — How to read these publications
How to read these publications
This selection carries forward references listed on the former Nexus site and organizes them by catalog entry. It is neither exhaustive nor a systematic assessment of evidence quality. Titles and links lead to publisher pages or bibliographic databases; consult the original paper to verify authors, date, study type, methods, and results.
2. Check the model studied
A cell experiment, an animal model, and a human study answer different questions. Conclusions are limited to the population, model, and context actually studied.
3. Examine methods and results
Look for comparison groups, measured outcomes, duration, stated limitations, and the results actually observed. Distinguish primary findings from hypotheses and interpretation.
4. Verify chemical matching
Compare the compound, sequence, variant, salt, or formulation studied with the exact catalog item. A similar name or linked paper does not confirm the contents or batch of a Nexus item.
02 — Catalog entries
Catalog entries
Publications listed under this catalog entry. Consult each source for its exact protocol and conclusions; a bibliographic association does not prove that a study concerns the Nexus variant or batch.
Source · PubMed Central · PMCID: PMC8337113
Roles of Nicotinamide N-Methyltransferase in Obesity
Source · PubMed Central · PMCID: PMC12054684
Nicotinamide N-Methyltransferase in Inflammatory Pathogenesis
Source · doi.org
Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice
Source · doi.org
Biomechanical stimulation effects on the metabolism of adipocyte
Source · doi.org
The Influence of Biologically Active Substances Secreted by the Adipose Tissue on Endometrial Cancer
No references are currently listed for this entry in the Nexus bibliography reviewed. This does not mean that no scientific literature exists.
Publications listed under this catalog entry. Consult each source for its exact protocol and conclusions; a bibliographic association does not prove that a study concerns the Nexus variant or batch.
Source · PubMed Central · PMCID: PMC12313605
Emerging Use of BPC-157 in Orthopaedic Sports Medicine
Source · PubMed · PMID: 40005999
Multifunctionality and Possible Medical Application of the BPC 157
Source · doi.org
Gastric pentadecapeptide body protection compound BPC 157 and its role in accelerating musculoskeletal soft tissue healing
Source · doi.org
Occluded Superior Mesenteric Artery and Vein. Therapy with the Stable Gastric Pentadecapeptide BPC 157
Source · doi.org
Pentadecapeptide BPC 157 resolves suprahepatic occlusion of the inferior caval vein, Budd-Chiari syndrome model in rats
Source · doi.org
BPC 157 as Potential Treatment for COVID-19
Source · doi.org
Pentadecapeptide BPC 157 and the central nervous system
Source · doi.org
Stable Gastric Pentadecapeptide BPC 157 Recovers Motor Function After Rat Spinal Cord Injury
Publications listed under this catalog entry. Consult each source for its exact protocol and conclusions; a bibliographic association does not prove that a study concerns the Nexus variant or batch.
Source · PubMed · PMID: 16822960
Once-daily administration of CJC-1295
Source · PubMed · PMID: 9849822
Ipamorelin, the first selective growth hormone secretagogue
Source · doi.org
Ipamorelin, the first selective growth hormone secretagogue
Publications listed under this catalog entry. Consult each source for its exact protocol and conclusions; a bibliographic association does not prove that a study concerns the Nexus variant or batch.
Source · doi.org
Epitalon protects against post-ovulatory aging-related damage of mouse oocytes in vitro
Source · doi.org
AEDG Peptide (Epitalon) Stimulates Gene Expression and Protein Synthesis during Neurogenesis: Possible Epigenetic Mechanism
Source · doi.org
Peptides and CCL11 and HMGB1 as molecular markers of aging: Literature review and own data
Source · doi.org
Pineal peptides restore the age-related disturbances in hormonal functions of the pineal gland and the pancreas
Source · PubMed · PMID: 12500162
Effect of epitalon on interleukin-1beta signal transduction and the reaction of thymocyte blast transformation under stress
Source · PubMed · PMID: 17217245
Intranasal Epitalon infusion modulates neuronal activity in the rat neocortex
Source · doi.org
Epithalon Peptide Induces Telomerase Activity and Telomere Elongation in Human Somatic Cells
Publications listed under this catalog entry. Consult each source for its exact protocol and conclusions; a bibliographic association does not prove that a study concerns the Nexus variant or batch.
Source · PubMed Central · PMCID: PMC6073405
Regenerative and Protective Actions of the GHK-Cu Peptide
Source · Frontiers
Exploring the beneficial effects of GHK-Cu
Source · doi.org
The tri-peptide GHK-Cu complex ameliorates lipopolysaccharide-induced acute lung injury in mice
Source · pubchem.ncbi.nlm.nih.gov
Glycyl-L-histidyl-L-lysine — PubChem CID 73587
Source · pubchem.ncbi.nlm.nih.gov
GHK-Cu — PubChem CID 133697840
Source · pubchem.ncbi.nlm.nih.gov
Copper tripeptide — PubChem CID 139035031
Publications listed under this catalog entry. Consult each source for its exact protocol and conclusions; a bibliographic association does not prove that a study concerns the Nexus variant or batch.
Source · PubMed Central · PMCID: PMC9947133
New insights on the cardiovascular effects of IGF-1
Source · PubMed Central · PMCID: PMC9380093
Insulin-like Growth Factor and its Therapeutic Potential
Source · doi.org
Attenuated glucose-stimulated insulin secretion during an acute IGF-1 LR3 infusion into fetal sheep does not persist in isolated islets
Source · pubchem.ncbi.nlm.nih.gov
Long-(Arg3)-insulin-like growth factor-I — PubChem substance record (CAS 143045-27-6; UNII M9L22Y19H9)
Source · bmrb.io
Long-[Arg3]-IGF-I — BMRB 4494, 83-residue sequence
Source · doi.org
Solution structure and backbone dynamics of long-[Arg(3)]insulin-like growth factor-I
Source · doi.org
Novel Demonstration of a Physiologic/Pharmacologic Role of Insulin-Like Growth Factor-1 in Ovulation in Rats and Action on Cumulus Oophorus
Source · doi.org
IGF-1 inhibits inflammation and accelerates angiogenesis via Ras/PI3K/IKK/NF-κB signaling pathways to promote wound healing
Source · doi.org
Reduced glucose-stimulated insulin secretion following a 1-wk IGF-1 infusion in late gestation fetal sheep is due to an intrinsic islet defect
Publications listed under this catalog entry. Consult each source for its exact protocol and conclusions; a bibliographic association does not prove that a study concerns the Nexus variant or batch.
Source · PubMed Central · PMCID: PMC3403564
Mechanism of KPV action and a role for MC3R agonists
Source · PubMed Central · PMCID: PMC5498804
Orally Targeted Delivery of Tripeptide KPV
Source · doi.org
A KPV-binding double-network hydrogel restores gut mucosal barrier in an inflamed colon
Source · doi.org
Melanocortin-derived tripeptide KPV has anti-inflammatory potential in murine models of inflammatory bowel disease
Source · PubMed · PMID: 22837805
Inhibition of cellular and systemic inflammation cues in human bronchial epithelial cells by melanocortin-related peptides: mechanism of KPV action and a role for MC3R agonists
Publications listed under this catalog entry. Consult each source for its exact protocol and conclusions; a bibliographic association does not prove that a study concerns the Nexus variant or batch.
Source · PubMed Central · PMCID: PMC9905433
MOTS-c: A promising mitochondrial-derived peptide
Source · Cell Press
The Mitochondrial-Derived Peptide MOTS-c Promotes Metabolic Homeostasis and Reduces Obesity and Insulin Resistance
Source · doi.org
MOTS-c promotes muscle differentiation in vitro
Source · doi.org
The Mitochondrial-Derived Peptide MOTS-c Alleviates Radiation Pneumonitis via an Nrf2-Dependent Mechanism
Source · doi.org
Central and peripheral mechanism of MOTS-c attenuates pain hypersensitivity in a mice model of inflammatory pain
Source · doi.org
Role of MOTS-c in the regulation of bone metabolism
Source · doi.org
Mitochondria-derived peptide MOTS-c: effects and mechanisms related to stress, metabolism and aging
Publications listed under this catalog entry. Consult each source for its exact protocol and conclusions; a bibliographic association does not prove that a study concerns the Nexus variant or batch.
Source · PubMed Central · PMCID: PMC9512238
The Role of NAD+ in Regenerative Medicine
Source · PubMed Central · PMCID: PMC7494058
NAD+ in Aging: Molecular Mechanisms
Source · doi.org
Evolving concepts in NAD+ metabolism
Source · doi.org
NAD+ and cardiovascular diseases
Source · doi.org
Bacteria boost host NAD metabolism
Source · doi.org
A Novel NAD Signaling Mechanism in Axon Degeneration and its Relationship to Innate Immunity
Source · doi.org
NAD+-dependent mechanism of pathological axon degeneration
Source · doi.org
Metabolically distinct roles of NAD synthetase and NAD kinase define the essentiality of NAD and NADP in Mycobacterium tuberculosis
Source · doi.org
The role of NAD and NAD precursors on longevity and lifespan modulation in the budding yeast, Saccharomyces cerevisiae
Source · doi.org
Enzymology of extracellular NAD metabolism
Publications listed under this catalog entry. Consult each source for its exact protocol and conclusions; a bibliographic association does not prove that a study concerns the Nexus variant or batch.
Source · doi.org
Retatrutide—A Game Changer in Obesity Pharmacotherapy
Source · doi.org
Triple hormone receptor agonist retatrutide for metabolic dysfunction-associated steatotic liver disease: a randomized phase 2a trial
Source · doi.org
Retatrutide showing promise in obesity (and type 2 diabetes)
Source · doi.org
7792 Efficacy of Retatrutide for Weight Reduction and Its Cardiometabolic Effects Among Adults: A Systematic Review and Meta-Analysis
Publications listed under this catalog entry. Consult each source for its exact protocol and conclusions; a bibliographic association does not prove that a study concerns the Nexus variant or batch.
Source · PubMed · PMID: 16635254
Semax, an analogue of adrenocorticotropin
Source · doi.org
Semax, an analog of ACTH(4−7), regulates expression of immune response genes during ischemic brain injury in rats
Source · doi.org
Effects of Semax on the Default Mode Network of the Brain
Source · doi.org
Audiogenic epilepsy in young mice of different strains after neonatal semax treatment
Source · doi.org
Semax for Epilepsy Treatment
Source · doi.org
Effects of Semax in the Rat Models of Acute Stress
Source · doi.org
The Potency of Semax Peptide Therapy toward MDA Level and Protein Profile in Epilepsy Rats (Rattus norvegicus)
Source · doi.org
SEMAX - APPLICATION PROSPECTS (brief overview message)
Source · PubMed · PMID: 9173745
Nootropic analogue of adrenocorticotropin 4-10-semax (the experience of design and investigation over 15 years)
Publications listed under this catalog entry. Consult each source for its exact protocol and conclusions; a bibliographic association does not prove that a study concerns the Nexus variant or batch.
Source · doi.org
Mitochondrial protein interaction landscape of SS-31
Source · PubMed Central · PMCID: PMC12779498
Elamipretide Improves Mitochondrial Function
Source · doi.org
SS31 Ameliorates Sepsis-Induced Heart Injury by Inhibiting Oxidative Stress and Inflammation
Source · doi.org
SS-31 Improves Cognitive Function in Sepsis-Associated Encephalopathy by Inhibiting the Drp1-NLRP3 Inflammasome Activation
Source · doi.org
Elamipretide mitigates ischemia-reperfusion injury in a swine model of hemorrhagic shock
Source · doi.org
The mitochondria-targeted peptide SS-31 binds lipid bilayers and modulates surface electrostatics as a key component of its mechanism of action
Source · doi.org
Molecular Mechanism of Action of Mitochondrial Therapeutic SS-31 (Elamipretide): Membrane Interactions and Effects on Surface Electrostatics
Source · doi.org
[Retracted] Mitochondrial‐Targeted Antioxidant Peptide SS31 Prevents RPE Cell Death under Oxidative Stress
Source · doi.org
Novel Mitochondria-Targeting Peptide in Heart Failure Treatment
Source · doi.org
SS31 alleviates LPS-induced acute lung injury by inhibiting inflammatory responses through the S100A8/NLRP3/GSDMD signaling pathway
Source · doi.org
Chronic administration of mitochondrion-targeted peptide SS-31 prevents atherosclerotic development in ApoE knockout mice fed Western diet
Source · doi.org
Mitochondria-Targeted Antioxidants and Skeletal Muscle Function
Publications listed under this catalog entry. Consult each source for its exact protocol and conclusions; a bibliographic association does not prove that a study concerns the Nexus variant or batch.
Source · PubMed · PMID: 22074294
Thymosin β4: a multi-functional regenerative peptide
Source · Springer Nature
Thymosin beta-4 improves endothelial function
Source · doi.org
Matrix metalloproteinases induce extracellular matrix degradation through various pathways to alleviate hepatic fibrosis
Source · doi.org
Promoting musculoskeletal system soft tissue regeneration by biomaterial-mediated modulation of macrophage polarization
Publications listed under this catalog entry. Consult each source for its exact protocol and conclusions; a bibliographic association does not prove that a study concerns the Nexus variant or batch.
Source · doi.org
Delineating tesamorelin response pathways in HIV-associated NAFLD using a targeted proteomic and transcriptomic approach
Source · doi.org
Tesamorelin for the treatment of excess abdominal fat in HIV-1-infected patients with lipodystrophy
Source · doi.org
Reduction in Visceral Adiposity Is Associated With an Improved Metabolic Profile in HIV-Infected Patients Receiving Tesamorelin
Source · doi.org